Globally, psychological well being problems and substance use problems (SUDs) contribute considerably to the general burden of illness, with many of those situations rising throughout adolescence. As soon as dismissed as mere “rising pains”, these situations considerably have an effect on high quality of life and social functioning. It has beforehand been estimated that every yr, round 25% of adolescents expertise a psychological well being dysfunction, rising to 33% over their lifetime (Kessler et al., 2007).
As emphasised by Beth Cumber in her recent Mental Elf blog, early intervention is critical for bettering psychological well being outcomes on this inhabitants. Equally, in his 2022 blog, Alejandro Arguelles Bullon highlighted the significance of age-stratified analyses to know threat patterns throughout adolescence, because it permits researchers to establish specific factors of vulnerability and potential intervention.
In opposition to this backdrop, Kieling et al. (2024) used the newest 2019 International Burden of Illness (GBD) information to analyse the worldwide prevalence and well being burden of psychological well being problems and substance use problems (SUDs) amongst totally different age teams throughout childhood and adolescence. Their findings reveal crucial traits of psychological well being problems throughout adolescence and provide clear instructions for early intervention, offering important proof for policymakers and healthcare employees.

The significance of early intervention and prevention in baby and adolescent psychological well being is more and more recognised, with age-stratified analyses permitting researchers to establish developments and factors of intervention.
Strategies
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) is a large inhabitants research that began within the early Nineteen Nineties to quantify ranges and developments in well being throughout the globe.
The present research by Kieling et al. (2024) analysed the worldwide prevalence and well being burden of psychological problems and SUDs amongst 2,516 million people aged 5–24 years utilizing information from the 2019 GBD research. Knowledge sources included nationwide well being surveys, hospital data, and worldwide experiences. Knowledge had been stratified by distinct age teams (5–9, 10–14, 15–19, and 20–24 years) and gender. Findings had been cross-validated with unbiased datasets to make sure reliability. The Explanation for Demise Ensemble Mannequin (CODEm) was carried out to regulate for comorbidities. Well being burden was quantified utilizing Years Lived with Incapacity (YLDs).
Outcomes
In 2019, 11.63% of people aged 5-24 years (roughly 293 million) had at the very least one psychological well being dysfunction, whereas 1.22% (roughly 31 million) had a SUD (see Desk 1 under). Nervousness problems had been essentially the most prevalent (3.35%; 84 million), and schizophrenia was the least frequent (0.08%; 2 million). Boys confirmed greater charges of neurodevelopmental problems similar to autism and attention-deficit hyperactivity dysfunction (ADHD), whereas women had higher prevalence of tension, temper, and consuming problems.
Relating to well being burden, psychological well being problems accounted for 20.27% (31.14 million of 153.59 million) of YLDs in youngsters and youths aged 5-24 years, the very best amongst all well being situations. SUDs contributed to 4.30 million YLDs. YLDs elevated dramatically with age, with nearly 5-fold will increase within the variety of YLDs within the age 20-24 years, in comparison with the age 5-9 years. Probably the most stark improve was for depressive problems, the place the variety of YLDs rose 35-fold from 5-9 years to 20-24 years.
From a broader life course perspective throughout all ages, 24.85% (31.14 million of 125.29 million) of whole YLDs related to psychological problems happen within the age 5 to 24 years, highlighting their important burden in comparison with different well being situations like cardiovascular illnesses (5.30%) and diabetes (3.15%).
Desk 1. Prevalence of at the very least one psychological well being dysfunction throughout age teams
Age group (years) | Prevalence (% [95% CI]) |
5 to 9 | 6.81% [5.60 to 8.03] |
10 to 14 | 12.42% [10.57 to 14.45] |
15 to 19 | 13.96% [12.37 to 15.78] |
20 to 24 | 13.63% [11.91 to 15.53] |
5 to 24 (all) | 11.63% (weighted imply) |

In 2019, roughly 293 million youngsters and adolescents aged 5-24 years skilled at the very least one psychological well being dysfunction, with anxiousness problems being essentially the most prevalent.
Conclusions
This research by Kieling and colleagues (2024) highlights the worldwide prevalence of psychological well being problems in youngsters and adolescents aged 5–24 years, with anxiousness problems and temper problems being the first contributors. Psychological well being problems account for 20.27% of non-fatal well being burdens from all GBD problems in people aged 5-24 years. Furthermore, over the life course, 24.85% of all well being burden attributable to psychological well being problems was present in individuals aged 5-24 years, reversing the everyday patterns noticed in different well being situations similar to cardiovascular illnesses and diabetes.
These psychological well being situations have a profound influence on training, social participation, and financial alternatives, with the burden notably excessive in low- and middle-income nations (LMICs). As such, this research emphasises the urgent want for an elevated give attention to early screening and intervention efforts, age-specific useful resource allocation, and prioritising adolescent psychological well being as a worldwide well being concern. Policymakers are urged to handle these challenges by evidence-based interventions and sustainable psychological well being insurance policies.

Between the ages of 5-9 and 20-24 years, the prevalence of getting at the very least one psychological well being dysfunction doubles, highlighting the significance of early intervention and prevention efforts throughout this developmental interval.
Strengths and limitations
Strengths
- The research adopts an age-stratified evaluation, providing detailed insights into psychological well being dysfunction prevalence and well being burden throughout distinct age teams throughout childhood and adolescence. It additionally offers evidence-based suggestions, emphasizing the significance of age-specific information for useful resource allocation and focused interventions.
- The research used the info from GBD, which is collected from throughout 204 nations and areas and consists of a variety of information sources, similar to systematic opinions, authorities experiences, and worldwide databases. This worldwide protection permits for cross-regional comparisons, supporting extra inclusive and culturally delicate well being insurance policies.
- The research employs a comorbidity adjustment mechanism to handle the overlap of a number of problems inside people, decreasing bias and making certain unbiased and correct estimates of every dysfunction’s burden throughout age, gender, and area.
Limitations
- Knowledge from LMICs are restricted in high quality, with over 170 million youngsters and youths residing in data-scarce areas. Moreover, high-risk teams similar to LGBTQIA+ youth and Indigenous adolescents are underrepresented. Such regional variations in information assortment and reporting additional have an effect on cross-region comparability.
- Knowledge sources range by age group, with parental experiences used for youthful youngsters and self-reports for adolescents, inflicting inconsistencies in information interpretation. Exclusion of subclinical displays additionally doubtlessly underestimates the true burden of psychological well being points.
- The research depends on 2019 cross-sectional information, limiting insights into longitudinal impacts of those psychological well being situations. Moreover, it doesn’t account for the influence of the COVID-19 pandemic, which had a widespread unfavourable influence on the psychological well being of youngsters and adolescents.
- Variations in diagnostic requirements, cultural perceptions, and reporting practices throughout areas might introduce observer bias, affecting the accuracy and comparability of prevalence estimates. Though the info had been adjusted to account for identified biases, there stays some uncertainty about their accuracy.

Whereas the usage of a worldwide dataset permits for cross-regional comparisons, there may be restricted information from low- and middle-income nations, alongside underrepresentation from high-risk teams.
Implications for follow
This research highlights the pressing want for early intervention and age-specific psychological well being methods at a worldwide scale. Insurance policies should prioritise ample funding, stigma discount, and accessible healthcare for kids and adolescents, particularly in LMICs.
Throughout my internship at a psychiatric hospital in China, I noticed that folks typically sought skilled assist solely when their youngsters’s tutorial efficiency had declined, and after a crucial incident, similar to self-harm or suicide. Earlier indicators of psychological misery had been ignored or not recognised. This lack of knowledge might result in delayed intervention, which may additional negatively influence tutorial efficiency, emotional stability, interpersonal relationships, and private growth, all of which I witnessed throughout my intervention.
Moreover, psychological well being stigma stays a serious barrier to well timed entry to skilled assist (Golberstein et al., 2008). Addressing psychological well being in childhood and adolescence requires not solely medical interventions however cultural shifts—fostering consciousness, acceptance, and proactive help programs all through society. This necessitates elevated communication between totally different programs, similar to colleges and healthcare providers.
Throughout my internship, I seen that colleges typically lacked the diagnostic instruments and coaching essential to establish and deal with psychological well being points at an early stage, whereas healthcare programs incessantly operated in isolation, with restricted communication and collaboration with colleges and households. This induced many missed alternatives for early intervention.

With a purpose to improve well timed entry to psychological well being help, we have to enhance consciousness of the early indicators of psychological misery in youngsters and adolescents.
Assertion of pursuits
None.
Hyperlinks
Main paper
Kieling, C., Buchweitz, C., Caye, A., Silvani, J., Ameis, S. H., Brunoni, A. R., … & Szatmari, P. (2024). Worldwide prevalence and disability from mental disorders across childhood and adolescence: evidence from the global burden of disease study. JAMA Psychiatry, 81(4), 347-356.
Different references
Bullon, A. A. (2022). Global burden of disease from mental disorders remains high. The Psychological Elf.
Cumber, B. (2024). Prevention is where it’s at for children and young people’s mental health. The Psychological Elf.
Golberstein, E., Eisenberg, D., & Gollust, S. E. (2008). Perceived stigma and mental health care seeking. Psychiatric Companies, 59(4), 392-399.
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, Okay. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of Basic Psychiatry, 62(6), 593-602.